This meta-analysis examined the association between 8-hydroxy-2-deoxyguanosine (8-OHdG) levels and cardiovascular disease (CVD), analyzing 14 studies with 810 CVD patients and 1,106 controls. Results showed significantly higher 8-OHdG levels in CVD patients compared to controls (standard mean difference: 1.04, 95% CI: 0.61–1.47, p < 0.001), with elevated levels observed in
