Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training

This randomized controlled trial evaluated the effects of weight loss, with or without exercise, on serum sclerostin levels and hip geometry in 107 obese adults aged ≥65 years. Participants were assigned to one of four groups: control, diet-induced weight loss, exercise, or combined diet-exercise, over 12 months. The diet group