Testosterone use in men and its effects on bone health. A systematic review and meta-analysis of randomized placebo-controlled trials

A meta-analysis published in The Journal of Clinical Endocrinology & Metabolism evaluated the effects of testosterone therapy on bone mineral density (BMD) in men by analyzing eight randomized placebo-controlled trials with 365 participants. The study found that intramuscular testosterone administration led to an 8% increase in lumbar spine BMD (95%