Well Referenced

Tag: Bone Mineral Density

Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial

This 2024 secondary analysis of a randomized clinical trial examined the effects of exercise, GLP-1 receptor agonist (liraglutide) treatment, and their combination on bone health in adults with obesity. After an initial 8-week low-calorie diet, 195 participants were randomized into four groups: exercise alone, liraglutide alone, combination of both, or

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June 26, 2025 No Comments

Progesterone and bone: actions promoting bone health in women

This 2010 review explores the role of progesterone in bone health, emphasizing its contribution to bone formation and maintenance in women. Progesterone stimulates osteoblast differentiation and, alongside estrogen, helps regulate bone remodeling. The article highlights that cyclic progestin therapy can prevent bone loss in premenopausal women with amenorrhea or subclinical

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June 26, 2025 No Comments

Hormonal therapy with estradiol and testosterone implants: bone protection?

This 2011 prospective cohort study assessed the impact of combined estradiol and testosterone implants on bone mineral density (BMD) in postmenopausal women. Sixty-one participants were divided into two groups: 34 women received hormone implants, while 27 did not undergo hormonal therapy. Over one year, the implant group maintained or slightly

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June 26, 2025 No Comments

Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases: A Systematic Review

The systematic review titled “Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases” (Mediterranean Journal of Rheumatology, 2023, DOI: 10.31138/mjr.20230825.dd) evaluated the effectiveness of DHEA in patients with systemic lupus erythematosus (SLE), Sjögren’s syndrome (SS), rheumatoid arthritis (RA), and fibromyalgia (FM) across 21 studies. DHEA supplementation notably improved bone mineral density, reduced fatigue,

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June 26, 2025 No Comments

Dehydroepiandrosterone sulfate and postmenopausal women

The systematic review titled “Dehydroepiandrosterone (DHEA) supplementation for women in the peri- or postmenopausal phase” (Current Opinion in Obstetrics and Gynecology, 2011, PMID: 21478748) assessed the benefits and safety of DHEA supplementation in peri- and postmenopausal women. Oral DHEA supplementation showed limited and inconsistent benefits, with mild improvements in bone

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June 26, 2025 No Comments

Dehydroepiandrosterone therapy as female androgen replacement

The article titled “Dehydroepiandrosterone therapy as female androgen replacement” (Seminars in Reproductive Medicine, 2006, PMID: 16633983) reviews the role of dehydroepiandrosterone (DHEA) supplementation as androgen replacement therapy in women, particularly focusing on menopausal and postmenopausal populations. It highlights potential improvements in sexual function, bone mineral density, mood, and overall well-being,

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June 26, 2025 No Comments

DHEA in bone: the role in osteoporosis and fracture healing

The review titled “DHEA in bone: the role in osteoporosis and fracture healing” (Archives of Osteoporosis, 2020, PMID: 32504237) examines the role of dehydroepiandrosterone (DHEA) in improving bone mineral density and potentially facilitating fracture healing. It highlights DHEA’s anabolic action on bone through stimulating osteoblast activity and increasing insulin-like growth

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June 26, 2025 No Comments