Tag: Bone Mineral Density

Bone Health After Exercise Alone, GLP-1 Receptor Agonist Treatment, or Combination Treatment: A Secondary Analysis of a Randomized Clinical Trial

This 2024 secondary analysis of a randomized clinical trial examined the effects of exercise, GLP-1 receptor agonist (liraglutide) treatment, and their combination on bone health in adults with obesity. After an initial 8-week low-calorie diet, 195 participants were randomized into four groups: exercise alone, liraglutide alone, combination of both, or

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Progesterone and bone: actions promoting bone health in women

This 2010 review explores the role of progesterone in bone health, emphasizing its contribution to bone formation and maintenance in women. Progesterone stimulates osteoblast differentiation and, alongside estrogen, helps regulate bone remodeling. The article highlights that cyclic progestin therapy can prevent bone loss in premenopausal women with amenorrhea or subclinical

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Hormonal therapy with estradiol and testosterone implants: bone protection?

This 2011 prospective cohort study assessed the impact of combined estradiol and testosterone implants on bone mineral density (BMD) in postmenopausal women. Sixty-one participants were divided into two groups: 34 women received hormone implants, while 27 did not undergo hormonal therapy. Over one year, the implant group maintained or slightly

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DHEA therapy for women: effect on sexual function and wellbeing

The review article “DHEA therapy for women: effect on sexual function and wellbeing” (Human Reproduction Update, 2007, PMID: 17208951) examines the effects of dehydroepiandrosterone (DHEA) supplementation on sexual function, cognition, and overall well-being in women. The findings suggest that DHEA modestly improves bone mineral density when combined with other treatments

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Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases: A Systematic Review

The systematic review titled “Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases” (Mediterranean Journal of Rheumatology, 2023, DOI: 10.31138/mjr.20230825.dd) evaluated the effectiveness of DHEA in patients with systemic lupus erythematosus (SLE), Sjögren’s syndrome (SS), rheumatoid arthritis (RA), and fibromyalgia (FM) across 21 studies. DHEA supplementation notably improved bone mineral density, reduced fatigue,

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Dehydroepiandrosterone sulfate and postmenopausal women

The systematic review titled “Dehydroepiandrosterone (DHEA) supplementation for women in the peri- or postmenopausal phase” (Current Opinion in Obstetrics and Gynecology, 2011, PMID: 21478748) assessed the benefits and safety of DHEA supplementation in peri- and postmenopausal women. Oral DHEA supplementation showed limited and inconsistent benefits, with mild improvements in bone

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Dehydroepiandrosterone therapy as female androgen replacement

The article titled “Dehydroepiandrosterone therapy as female androgen replacement” (Seminars in Reproductive Medicine, 2006, PMID: 16633983) reviews the role of dehydroepiandrosterone (DHEA) supplementation as androgen replacement therapy in women, particularly focusing on menopausal and postmenopausal populations. It highlights potential improvements in sexual function, bone mineral density, mood, and overall well-being,

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