Tag: meta-analysis

The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials

This 2020 systematic review and meta-analysis evaluated the effects of berberine supplementation on obesity-related parameters, inflammation, and liver function enzymes. Analyzing 12 randomized controlled trials, the study found that berberine intake led to significant reductions in body weight (mean difference: -2.07 kg), body mass index (BMI), waist circumference, and C-reactive

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Shock-wave therapy versus corticosteroid injection on lateral epicondylitis: a meta-analysis of randomized controlled trials

This 2019 meta-analysis evaluated the efficacy of extracorporeal shock wave therapy (ESWT) compared to corticosteroid (CS) injections in treating lateral epicondylitis (LE). Analyzing four randomized controlled trials, the study found that ESWT significantly improved pain intensity (VAS) and grip strength over CS injections at follow-ups beyond 12 weeks. Specifically, ESWT

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The Effect of Extracorporeal Shock Wave Therapy on Pain Intensity and Neck Disability for Patients With Myofascial Pain Syndrome in the Neck and Shoulder: A Meta-Analysis of Randomized Controlled Trials

This 2021 meta-analysis evaluated the efficacy of extracorporeal shock wave therapy (ESWT) in treating myofascial pain syndrome (MPS) of the neck and shoulder. Analyzing 11 randomized controlled trials, the study found that ESWT significantly improved pain intensity (SMD = 0.67; 95% CI: 0.11 to 1.23; P = 0.02) and pressure

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The efficacy and safety of extracorporeal shockwave therapy in knee osteoarthritis: A systematic review and meta-analysis

This 2020 systematic review and meta-analysis evaluated the efficacy and safety of extracorporeal shockwave therapy (ESWT) in treating knee osteoarthritis (KOA). Analyzing three randomized controlled trials and three cohort studies encompassing 589 patients, the study found that ESWT significantly reduced pain scores at 4, 8, and 12 weeks post-treatment, with

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Extracorporeal Shock Wave Therapy for the Treatment of Osteoarthritis: A Systematic Review and Meta-Analysis

This 2020 systematic review and meta-analysis evaluated the efficacy and safety of extracorporeal shock wave therapy (ESWT) in treating osteoarthritis (OA). The analysis included randomized controlled trials comparing ESWT with other treatments such as placebo, corticosteroids, hyaluronic acid, medications, ultrasound, kinesiotherapy, moxibustion, acupotomy surgery, platelet-rich plasma, fumigation, and manipulation. ESWT

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The efficacy and safety of low-intensity extracorporeal shock wave treatment combined with or without medications in Chronic prostatitis/chronic pelvic pain syndrome: a systematic review and meta-analysis

This 2023 systematic review and meta-analysis evaluated 12 randomized controlled trials involving 651 patients to assess the efficacy and safety of low-intensity extracorporeal shock wave therapy (Li-ESWT), alone or combined with medications, for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). Li-ESWT significantly improved NIH-CPSI total, pain, and quality of life scores

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Serious Adverse Events of Cell Therapy for Respiratory Diseases: A Systematic Review and Meta-Analysis

This systematic review and meta-analysis assessed the safety profile of cell-based therapies in respiratory diseases by analyzing 23 clinical studies involving 204 patients with conditions such as ARDS, COPD, IPF, PAH, and others. The findings indicated that both systemic infusions and bronchial instillations of mesenchymal stem/stromal or progenitor cells were

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Concise Review: Stem Cell Interventions for People With Cerebral Palsy: Systematic Review With Meta-Analysis

This systematic review and meta-analysis evaluated the efficacy and safety of stem cell therapies in individuals with cerebral palsy (CP). Analyzing five clinical trials encompassing 328 participants, the study examined various stem cell types, including olfactory ensheathing cells, neural stem cells, neural progenitors, and allogeneic umbilical cord blood cells. The

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Safety and Efficacy of Adult Stem Cell Therapy for Acute Myocardial Infarction and Ischemic Heart Failure (SafeCell Heart): A Systematic Review and Meta-Analysis

This systematic review and meta-analysis evaluated the safety and efficacy of mesenchymal stem cell (MSC) therapy in adults with acute myocardial infarction (AMI) and ischemic heart failure (IHF). Analyzing 23 clinical trials (11 on AMI and 12 on IHF), the study found that MSC therapy was not associated with acute

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