This 2017 review discusses the roles of resveratrol (RES), curcumin (CUR), and berberine (BBR) in modulating aging, cancer progression, cancer stem cells (CSCs), and microRNA (miR) expression. RES activates sirtuins (e.g., SIRT1), influencing aging and cancer-related pathways. CUR exhibits anti-inflammatory and anti-cancer properties, particularly against CSCs, by affecting gene methylation
