This systematic review examines the role of mitochondrial dysfunction in various neurodegenerative diseases—such as Parkinson’s disease, Alzheimer’s disease, ALS, multiple system atrophy, and progressive supranuclear palsy—and explores the potential benefits of nutritional supplementation with CoQ10, B-vitamins/NADH, L-carnitine, vitamin D, and alpha-lipoic acid. These nutrients are proposed to support mitochondrial ATP
