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Tag: amyotrophic lateral sclerosis

Mitochondrial Dysfunction and Neurodegenerative Disorders: Role of Nutritional Supplementation

This systematic review examines the role of mitochondrial dysfunction in various neurodegenerative diseases—such as Parkinson’s disease, Alzheimer’s disease, ALS, multiple system atrophy, and progressive supranuclear palsy—and explores the potential benefits of nutritional supplementation with CoQ10, B-vitamins/NADH, L-carnitine, vitamin D, and alpha-lipoic acid. These nutrients are proposed to support mitochondrial ATP

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June 26, 2025 No Comments

Dysregulation of glutathione homeostasis in neurodegenerative diseases

The article “Dysregulation of glutathione homeostasis in neurodegenerative diseases” (Nutrients, 2012, PMID: 23201762) is a review that examines how disruptions in glutathione (GSH) balance contribute to the development and progression of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, and Huntington’s diseases, as well as amyotrophic lateral sclerosis and Friedreich’s ataxia. The

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June 26, 2025 No Comments