This 2018 review examines the role of the PI3K/AKT/mTOR pathway in the development and progression of pulmonary fibrosis, particularly idiopathic pulmonary fibrosis (IPF) and radiation-induced pulmonary fibrosis (RIPF). It outlines how mTOR dysregulation contributes to fibroblast proliferation, suppression of autophagy, chronic inflammation, and epithelial-mesenchymal transition (EMT), all of which drive
