Dehydroepiandrosterone, Cancer, and Aging

The review article titled "Dehydroepiandrosterone, Cancer, and Aging" (Aging and Disease, 2022, PMID: 35430962) evaluates the potential benefits of dehydroepiandrosterone (DHEA), the most abundant circulating steroid hormone, in preventing and managing age-related diseases, particularly cancer and metabolic disorders. It highlights DHEA’s proposed mechanism of action, including inhibition of glucose-6-phosphate dehydrogenase