The article titled "Decrypting the potential role of α-lipoic acid in Alzheimer's disease" (Life Sciences, 2021, PMID: 34450170) reviews the neuroprotective effects of alpha-lipoic acid (α-LA) in Alzheimer's disease (AD), which is characterized by amyloid-β plaques, tau protein accumulation, oxidative stress, and mitochondrial dysfunction. The review highlights α-LA’s antioxidant, antiapoptotic,