Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus

This study examined the antidepressant-like effects of chronic administration of synthetic cannabidiol (CBD) in mice. Over seven days, mice received CBD at doses of 10, 30, or 100 mg/kg, and depressive-like behaviors were assessed using the forced swim test (FST). The study found that 100 mg/kg of CBD significantly reduced