This cohort study evaluated the reliability of serum biomarkers for chronic inflammation (CI) in older adults, comparing soluble tumor necrosis factor receptor 1 (sTNFR1) with interleukin-6 (IL-6). Results showed that sTNFR1 had significantly greater reproducibility over time, with intra-class correlation coefficients (ICC) of 0.95 at 6 weeks and 0.79 at
