α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage

This 2017 in vivo and in vitro study published in Cell Physiology and Biochemistry (DOI: 10.1159/000481840, PMID: 28992629) investigated the neuroprotective effects of alpha-lipoic acid (ALA) in models of ischemic stroke. Administered after middle cerebral artery occlusion in rats, ALA significantly reduced infarct volume, brain edema, and oxidative stress while