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Tag: brain recovery

α-Lipoic Acid Promotes Neurological Recovery After Ischemic Stroke by Activating the Nrf2/HO-1 Pathway to Attenuate Oxidative Damage

This 2017 in vivo and in vitro study published in Cell Physiology and Biochemistry (DOI: 10.1159/000481840, PMID: 28992629) investigated the neuroprotective effects of alpha-lipoic acid (ALA) in models of ischemic stroke. Administered after middle cerebral artery occlusion in rats, ALA significantly reduced infarct volume, brain edema, and oxidative stress while

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June 26, 2025 No Comments

Α‑lipoic acid protects against cerebral ischemia/reperfusion-induced injury in rats

This 2015 study published in Molecular Medicine Reports (DOI: 10.3892/mmr.2015.3170, PMID: 25572614) explored the neuroprotective effects of alpha-lipoic acid (ALA) in a rat model of cerebral ischemia/reperfusion (I/R) injury. The results showed that ALA treatment significantly reduced infarct size, improved neurological deficits, and decreased oxidative stress markers, including malondialdehyde (MDA)

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June 26, 2025 No Comments