Testosterone Therapy is Associated With Depression, Suicidality, and Intentional Self-Harm: Analysis of a National Federated Database

This meta-analysis and Mendelian randomization study explored the association between serum testosterone levels and depression in women, finding a significant correlation, particularly in premenopausal women, but only borderline significance in postmenopausal women. However, no causal relationship was established between testosterone levels and depression, suggesting that testosterone supplementation should not be