Well Referenced

Tag: Hormone levels

[Effects of various contraceptives on laboratory parameters in diagnosis of thyroid gland function with special reference to the free hormones FT4 and FT3]

This observational study examined the effects of various contraceptives on laboratory assessments of thyroid function, focusing on free thyroxine (FT4) and free triiodothyronine (FT3) levels. The findings indicate that contraceptive use, particularly those containing estrogen, can influence thyroid hormone measurements by increasing thyroid-binding globulin levels, potentially altering free hormone concentrations.

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June 26, 2025 No Comments

Testosterone Therapy is Associated With Depression, Suicidality, and Intentional Self-Harm: Analysis of a National Federated Database

This meta-analysis and Mendelian randomization study explored the association between serum testosterone levels and depression in women, finding a significant correlation, particularly in premenopausal women, but only borderline significance in postmenopausal women. However, no causal relationship was established between testosterone levels and depression, suggesting that testosterone supplementation should not be

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June 26, 2025 No Comments

Age-specific reference ranges for serum testosterone and androstenedione concentrations in women measured by liquid chromatography-tandem mass spectrometry

This study establishes age-specific reference ranges for serum testosterone and androstenedione in women, using liquid chromatography-tandem mass spectrometry. The results indicate a significant age-related decline in these hormones, with reference ranges provided for each age group. These findings can assist clinicians in more accurately diagnosing and monitoring hormone-related conditions in

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June 26, 2025 No Comments

Do estradiol levels influence on the cognitive function during antidepressant treatments in post-menopausal women with major depressive disorder? A comparison with pre-menopausal women

This observational study examined the impact of estradiol (E2) levels on cognitive function during antidepressant treatment in 39 women with major depressive disorder (MDD), comparing pre-menopausal and post-menopausal groups. Over a 6-week period, cognitive function improved significantly across all participants (P=0.00001), but in post-menopausal women, higher E2 levels were strongly

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June 26, 2025 No Comments