This 2021 systematic review compiles findings from 2010–2020 on the role of Coenzyme Q₁₀ (CoQ₁₀) in human health and disease, emphasizing its antioxidant, anti-inflammatory, and mitochondrial bioenergetic functions. It outlines evidence for CoQ₁₀'s effectiveness in improving cardiovascular health (notably heart failure outcomes and endothelial function), fertility (enhanced reproductive parameters), skeletal
