Progesterone prevents sleep disturbances and modulates GH, TSH, and melatonin secretion in postmenopausal women

This randomized, double-blind, placebo-controlled study evaluated the effects of 300 mg of oral progesterone administered nightly for three weeks on sleep architecture and hormonal profiles in healthy postmenopausal women. The results indicated that while progesterone did not affect undisturbed sleep, it significantly improved sleep disturbances caused by blood sampling, reducing