Progestagen component in combined hormone replacement therapy in postmenopausal women and breast cancer risk: a debated clinical issue

This study examines the impact of different progestagens in hormone replacement therapy (HRT) on breast cancer risk among postmenopausal women. Published in Gynecological Endocrinology (2009), it discusses how various progestins may influence breast cancer cell behavior differently, with some evidence suggesting that certain progestins could enhance the proliferation and invasiveness