Well Referenced

Tag: estrogen-progestin therapy

Progestagen component in combined hormone replacement therapy in postmenopausal women and breast cancer risk: a debated clinical issue

This study examines the impact of different progestagens in hormone replacement therapy (HRT) on breast cancer risk among postmenopausal women. Published in Gynecological Endocrinology (2009), it discusses how various progestins may influence breast cancer cell behavior differently, with some evidence suggesting that certain progestins could enhance the proliferation and invasiveness

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June 26, 2025 No Comments

Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis

A systematic review and meta-analysis published in Fertility and Sterility (2017) evaluated the efficacy and safety of transdermal testosterone therapy in postmenopausal women with hypoactive sexual desire disorder (HSDD). The study found that transdermal testosterone significantly improved sexual function in both naturally and surgically menopausal women, regardless of concurrent estrogen-progestin

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June 26, 2025 No Comments

Influence of estrogen-progestin treatment on back pain and disability among slim premenopausal women with low lumbar spine bone mineral density. A 2-year placebo-controlled randomized trial

This randomized controlled trial examined the effects of estrogen-progestin therapy on back pain and functional disability in slim premenopausal women with low lumbar spine bone mineral density (BMD). Among 48 participants, those receiving hormone therapy experienced significant reductions in nighttime back pain (p < 0.001) and Oswestry disability scores (p

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June 26, 2025 No Comments