This 2013 observational study evaluated the effects of long-term testosterone therapy in 261 hypogonadal men aged 32–84 years. Participants received parenteral testosterone undecanoate 1000 mg every 12 weeks over a 5-year period. Results demonstrated progressive and sustained reductions in body weight (from 100.1 ± 14.0 kg to 92.5 ± 11.2