This 24-week randomized, double-blind, placebo-controlled trial evaluated the effects of 1000 μg/day chromium picolinate supplementation, alone and with passive nutritional education, on weight loss in 80 overweight adults. Participants were randomized to receive chromium picolinate or placebo; all received nutritional education at week 12. No significant differences were observed in
This 2022 systematic review and meta-analysis compared intermittent fasting (IF) and continuous calorie restriction (CCR) in overweight and obese adults. Analyzing randomized clinical trials, the study found that IF led to a modestly greater weight loss than CCR (standardized mean difference [SMD] = -0.21; 95% CI: -0.40 to -0.02; p
This longitudinal study analyzed data from 6,514 U.S. adults born between 1931 and 1941, who were free of clinically relevant depressive symptoms in 1994. Over a 16-year follow-up period, the study found that overweight and obese individuals had a higher risk of developing depression compared to those with normal weight.
This retrospective study analyzed 529 overweight and obese patients (BMI ≥25 kg/m²) enrolled in a cardiac rehabilitation and exercise training (CRET) program following major coronary events. Patients were divided based on median weight change: those with greater weight loss (mean -5%) and those with less or no weight loss (mean
This 2012 cross-sectional study evaluated 1,393 adults (63% female, mean age 51.4 years) to compare BMI, percent body fat (via DXA), and leptin levels in assessing obesity. While BMI identified 26% as obese, DXA revealed 64% were obese, indicating BMI underestimated obesity prevalence. Notably, 39% were misclassified as non-obese by
This 2013 cross-sectional study assessed 976 adults (414 obese, 212 overweight, 351 controls) in a primary care setting to examine the relationship between vitamin B12 levels and metabolic parameters. Findings revealed significantly lower vitamin B12 levels in obese (178.9 ± 25.2 pg/mL) and overweight (219.8 ± 78.5 pg/mL) individuals compared
This 2009 meta-analysis by the Prospective Studies Collaboration pooled data from 57 prospective studies involving 894,576 adults, primarily from Western Europe and North America. The study investigated the relationship between body mass index (BMI) and cause-specific mortality. Findings indicated that the lowest mortality risk was observed in individuals with a
This 2014 population-based cohort study analyzed 1,857,822 singleton live births in Sweden from 1992 to 2010 to assess the association between maternal BMI in early pregnancy and infant mortality. Compared to normal-weight women (BMI 18.5–24.9), overweight (BMI 25.0–29.9) and obesity grade 1 (BMI 30.0–34.9) were associated with modestly increased risks
The 2023 Indian Academy of Pediatrics (IAP) guidelines update the 2004 recommendations on childhood obesity, addressing the rising prevalence and evolving understanding of its pathogenesis and management. The guidelines emphasize distinguishing primary (exogenous) from secondary (endogenous) obesity, as management strategies differ. For diagnosis, weight-for-length/height using WHO charts is recommended for
A 12-week double-blind, randomized, placebo-controlled trial evaluated the impact of black soy peptide (BSP) supplementation on body composition in overweight and obese adults (n=80). Participants received either BSP (4.5 g/day) or placebo. The BSP group showed significant reductions in body weight, BMI, body fat mass, and body fat percentage compared
