Well Referenced

Tag: waist circumference

Effects of oral α-lipoic acid administration on body weight in overweight or obese subjects: a crossover randomized, double-blind, placebo-controlled trial

This 2017 randomized, double-blind, placebo-controlled crossover trial evaluated the effects of α-lipoic acid (ALA) supplementation on body weight in overweight or obese individuals. A total of 103 Chinese Han participants with a BMI ≥25 kg/m² were randomized to receive either 1200 mg/day of ALA or placebo for 8 weeks, followed

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June 26, 2025 No Comments

Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis

This 2018 systematic review and network meta-analysis evaluated the impact of FDA-approved weight-loss medications—phentermine-topiramate, liraglutide, naltrexone-bupropion, lorcaserin, and orlistat—on cardiometabolic risk factors in obese adults. Analyzing 28 randomized controlled trials encompassing 29,018 participants, the study found that these medications led to modest reductions in fasting blood glucose (mean decrease of

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June 26, 2025 No Comments

A Pilot Study Investigating the Effect of Caralluma Fimbriata Extract on the Risk Factors of Metabolic Syndrome in Overweight and Obese Subjects: A Randomised Controlled Clinical Trial

This 12-week randomized, double-blind, placebo-controlled clinical trial assessed the effects of Caralluma fimbriata extract on metabolic syndrome risk factors in 33 overweight and obese adults. Participants received 1 g/day of Caralluma fimbriata extract or placebo, alongside controlled dietary intake and physical activity. The Caralluma group experienced a greater reduction in

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June 26, 2025 No Comments

Effects of Exercise Amount and Intensity on Abdominal Obesity and Glucose Tolerance in Obese Adults: A Randomized Trial

This 2015 randomized controlled trial assessed the independent effects of exercise amount and intensity on abdominal obesity and glucose tolerance in 300 abdominally obese adults over 24 weeks. Participants were assigned to one of four groups: control (no exercise), low-amount low-intensity (LALI), high-amount low-intensity (HALI), or high-amount high-intensity (HAHI) exercise.

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June 26, 2025 No Comments

Isolated Aerobic Exercise and Weight Loss: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

This 2011 systematic review and meta-analysis evaluated the efficacy of isolated aerobic exercise programs in overweight and obese populations. Analyzing 14 randomized controlled trials encompassing 1,847 participants, the study found that moderate-intensity aerobic exercise over 6 to 12 months led to modest reductions in weight (approximately 1.6–1.7 kg) and waist

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June 26, 2025 No Comments

Validity of Segmental Multiple-Frequency Bioelectrical Impedance Analysis to Estimate Body Composition of Adults Across a Range of Body Mass Indexes

This 2009 cross-sectional study assessed the accuracy of eight-electrode segmental multiple-frequency bioelectrical impedance analysis (MF-BIA) in estimating body composition compared to dual-energy X-ray absorptiometry (DXA) in 132 healthy adults categorized as normal weight (BMI 18.5–24.9), overweight (BMI 25–29.9), and obese (BMI 30–39.9). MF-BIA overestimated body fat percentage (%BF) in obese

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June 26, 2025 No Comments

Adiposity and Risk of Decline in Glomerular Filtration Rate: Meta-analysis of Individual Participant Data in a Global Consortium

This 2019 individual participant data meta-analysis pooled data from over 5.4 million adults across 39 general population cohorts, 6 high cardiovascular risk cohorts, and 18 chronic kidney disease (CKD) cohorts spanning 40 countries. The study assessed associations between adiposity measures—body mass index (BMI), waist circumference, and waist-to-height ratio—and decline in

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June 26, 2025 No Comments

Indian Academy of Pediatrics Revised Guidelines on Evaluation, Prevention and Management of Childhood Obesity

The 2023 Indian Academy of Pediatrics (IAP) guidelines update the 2004 recommendations on childhood obesity, addressing the rising prevalence and evolving understanding of its pathogenesis and management. The guidelines emphasize distinguishing primary (exogenous) from secondary (endogenous) obesity, as management strategies differ. For diagnosis, weight-for-length/height using WHO charts is recommended for

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June 26, 2025 No Comments

A Natural Fiber Complex Reduces Body Weight in Overweight and Obese Adults

This 2013 double-blind, randomized, placebo-controlled study evaluated the efficacy and safety of Litramine IQP-G-002AS, a natural fiber complex derived from Opuntia ficus-indica, in promoting weight loss among 125 overweight and obese adults. Participants received either 3 g/day of Litramine or a placebo for 12 weeks, alongside nutritional counseling and a

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June 26, 2025 No Comments