L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial

This randomized, double-blind, placebo-controlled trial investigated the effects of L-carnitine supplementation on physical and mental fatigue, cognitive function, and body composition in centenarians. Participants receiving 2 grams of levocarnitine daily experienced significant reductions in fat mass (-1.80 kg vs. +0.6 kg; P < 0.01), increases in muscle mass (+3.80 kg