Elevated Levels of Circulating Biomarkers Related to Leaky Gut Syndrome and Bacterial Translocation Are Associated With Graves’ Disease

This 2021 observational study published in Frontiers in Endocrinology (PMID: 34975767) explored the connection between intestinal barrier dysfunction and Graves' disease (GD). In 91 patients with GD compared to 44 healthy controls, researchers found significantly elevated serum levels of lipopolysaccharide (LPS), intestinal fatty acid-binding protein (I-FABP), zonulin, and D-lactate (p