Tag: thyroid autoimmunity

Association of Depression and Anxiety Disorders With Autoimmune Thyroiditis: A Systematic Review and Meta-analysis

This 2018 systematic review and meta-analysis evaluated the link between autoimmune thyroiditis (AIT) and mood disorders, specifically depression and anxiety. The analysis included 19 studies comprising over 36,000 individuals. Results showed that patients with AIT, including Hashimoto’s thyroiditis, had a 3.56-fold increased odds of depression and a 2.32-fold increased odds

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Assessment and Treatment of Thyroid Disorders in Pregnancy and the Postpartum Period

This 2022 review provides updated clinical guidance on the assessment and management of thyroid disorders during pregnancy and the postpartum period. Key considerations include the increased iodine requirement due to heightened thyroid hormone production, and the differentiation between gestational transient thyrotoxicosis and Graves’ disease in early pregnancy. The review addresses

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Elevated Levels of Circulating Biomarkers Related to Leaky Gut Syndrome and Bacterial Translocation Are Associated With Graves’ Disease

This 2021 observational study published in Frontiers in Endocrinology (PMID: 34975767) explored the connection between intestinal barrier dysfunction and Graves’ disease (GD). In 91 patients with GD compared to 44 healthy controls, researchers found significantly elevated serum levels of lipopolysaccharide (LPS), intestinal fatty acid-binding protein (I-FABP), zonulin, and D-lactate (p

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Overt and subclinical hypothyroidism: who to treat and how

The article “Overt and subclinical hypothyroidism: who to treat and how” discusses the treatment strategies for overt and subclinical hypothyroidism, emphasizing that all patients with overt hypothyroidism and those with subclinical hypothyroidism with thyroid-stimulating hormone (TSH) levels exceeding 10 mIU/L should receive treatment. It highlights the importance of treating pregnant

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