Elevated fecal calprotectin is associated with gut microbial dysbiosis, altered serum markers and clinical outcomes in older individuals

This observational study of 735 older adults found that elevated fecal calprotectin levels correlated with gut microbial dysbiosis, higher pro-inflammatory serum markers, and increased prevalence of conditions like obesity and heart attacks. Participants with fecal calprotectin levels above 100 μg/g exhibited significant changes in gut microbiota, reduced short-chain fatty acid-producing