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Tag: fecal calprotectin

From bench to bedside: Fecal calprotectin in inflammatory bowel diseases clinical setting

This review highlights the utility of fecal calprotectin (FC) as a non-invasive biomarker for managing inflammatory bowel diseases (IBD). It describes FC’s role in differentiating IBD from irritable bowel syndrome (IBS), monitoring disease activity, predicting relapses, and evaluating treatment response. Although FC levels correlate well with mucosal healing and histology,

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June 26, 2025 No Comments

Calprotectin: from biomarker to biological function

This review discusses the multifaceted role of calprotectin (CP) as both a biomarker and an active player in immune modulation and antimicrobial defense. CP is commonly used to assess gastrointestinal inflammation, particularly in inflammatory bowel diseases (IBD), and its concentration can help distinguish between inflammatory and non-inflammatory conditions. The review

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June 26, 2025 No Comments

Elevated fecal calprotectin is associated with gut microbial dysbiosis, altered serum markers and clinical outcomes in older individuals

This observational study of 735 older adults found that elevated fecal calprotectin levels correlated with gut microbial dysbiosis, higher pro-inflammatory serum markers, and increased prevalence of conditions like obesity and heart attacks. Participants with fecal calprotectin levels above 100 μg/g exhibited significant changes in gut microbiota, reduced short-chain fatty acid-producing

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June 26, 2025 No Comments