This comprehensive review examines the biological functions and therapeutic potential of choline-containing phospholipids (CCPLs), particularly CDP-choline (citicoline) and choline alphoscerate (α-GPC), in brain health. CCPLs are vital components of cell membranes and precursors to acetylcholine, essential for cholinergic neurotransmission. They also contribute to membrane repair, signal transduction, and methylation pathways.
