Acute effects of Nitrosigine® and citrulline malate on vasodilation in young adults

This randomized controlled trial examined the effects of Nitrosigine® (arginine and silicon) and citrulline malate (CM) on endothelial-dependent vasodilation in 24 healthy, physically active adults. Participants consumed either 1.5 g of Nitrosigine®, 8 g of CM, or a placebo, with flow-mediated dilation (FMD) measured before and 60 minutes post-ingestion. Both