This experimental study evaluates α-lipoic acid (LA) as a modulator of copper homeostasis in Alzheimer's disease (AD). Through in vitro and in vivo models—including SH-SY5Y neuronal cells and Drosophila melanogaster expressing human Aβ—LA was found to promote intracellular copper uptake, potentially reversing the copper dyshomeostasis observed in AD. Supplementation with
