Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study

A cohort study published in Lancet Oncology (2008) examined the role of tumor hypoxia and angiogenesis markers in predicting the outcome of radical treatments for localized prostate cancer. The study found that high expression levels of VEGF and HIF-1α were linked to shorter biochemical failure-free survival in both radiotherapy and