Well Referenced

Tag: angiogenesis

Enhanced Spinal Therapy: Extracorporeal Shock Wave Therapy for the Spine

This 2020 narrative review examines the application of extracorporeal shock wave therapy (ESWT) in treating various spinal pathologies. The review highlights ESWT’s potential benefits in conditions such as degenerative osteoporotic neuro-spinal pathology, heterotopic ossification due to spinal cord injury, cervical spondylosis, scoliosis, sacroiliitis, and coccydynia. ESWT is noted to upregulate

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June 26, 2025 No Comments

Erectile Dysfunction Treatment Using Stem Cells: A Review

This 2021 systematic review evaluated clinical studies on stem cell therapy (SCT) for erectile dysfunction (ED), highlighting its potential as a regenerative treatment. Various stem cell types—adipose-derived (ADSC), bone marrow-derived (BMSC), umbilical cord, and placental—have been administered primarily via intracavernosal injection. Clinical trials reported improvements in erectile function, with some

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June 26, 2025 No Comments

Hyperbaric oxygen therapy in radionecrotic lesions

This 1982 study investigated the application of hyperbaric oxygen therapy (HBOT) in treating radionecrotic lesions resulting from radiation therapy. HBOT involves administering 100% oxygen at elevated atmospheric pressures to enhance tissue oxygenation, promote angiogenesis, and facilitate healing in hypoxic tissues. The study reported that HBOT led to significant improvements in

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June 26, 2025 No Comments

Striated, Smooth, and Heart Muscle

This 2022 review article explores the therapeutic potential of the stable gastric pentadecapeptide BPC 157 in the regeneration and functional recovery of striated, smooth, and cardiac muscles. BPC 157 demonstrates cytoprotective properties that facilitate healing in various muscle injuries, including myotendinous junction disruptions, by promoting angiogenesis, fibroblast proliferation, and collagen

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June 26, 2025 No Comments

Induction of dermal collagenesis, angiogenesis, and adipogenesis in human skin by injection of platelet-rich fibrin matrix

This clinical trial assessed the histological effects of autologous platelet-rich fibrin matrix (PRFM) injections in human skin. Four healthy adult volunteers received PRFM injections into the deep dermis and subdermis of the upper arms. Biopsies over a 10-week period revealed early fibroblast activation and collagen deposition by day 7, angiogenesis

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June 26, 2025 No Comments

The acute effects of preoperative ozone therapy on surgical wound healing

This 2016 animal study assessed the impact of preoperative rectal ozone insufflation on surgical wound healing in rabbits. Twenty-one rabbits were divided into three groups: sham, surgical wound without treatment, and surgical wound with ozone therapy (70 µg/mL O₂-O₃ mixture, 12 mL, administered rectally every other day for six sessions).

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June 26, 2025 No Comments

Hyperbaric oxygen therapy and cancer—a review

This 2012 review by Moen and Stuhr examines the effects of hyperbaric oxygen therapy (HBOT) on cancer progression, focusing on studies from 2004 to 2012. The authors found no evidence that HBOT stimulates tumor growth or recurrence. Instead, HBOT may inhibit tumor growth in certain cancer subtypes, such as breast

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June 26, 2025 No Comments

Angiogenesis and lead (Pb): is there a connection?

This review explores the potential link between lead (Pb) exposure and angiogenesis, the process of new blood vessel formation. Epidemiological and experimental studies suggest that Pb exposure may disrupt the regulation of angiogenic factors, particularly vascular endothelial growth factor (VEGF), leading to either excessive or insufficient angiogenesis. Such dysregulation is

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June 26, 2025 No Comments

Therapeutic Effects of Artesunate in Hepatocellular Carcinoma: Repurposing an Ancient Antimalarial Agent

This preclinical study investigated the anticancer properties of artesunate, a semisynthetic artemisinin derivative, in hepatocellular carcinoma (HCC). Artesunate significantly inhibited cell viability and induced caspase-3-mediated apoptosis in HCC cell lines (HepG2, BWTG3), with more pronounced effects under hypoxic conditions. It also suppressed angiogenic markers VEGF and placental growth factor, leading

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June 26, 2025 No Comments