Well Referenced

Tag: postmenopausal women

The current outlook for testosterone in the management of hypoactive sexual desire disorder in postmenopausal women

A review published in The Journal of Sexual Medicine examined the role of testosterone therapy in managing hypoactive sexual desire disorder (HSDD) in postmenopausal women. The study found that testosterone treatment significantly improves sexual desire and satisfaction in this population. However, potential side effects such as hirsutism and acne were

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June 26, 2025 No Comments

The effects of hormone replacement therapy on sleep-disordered breathing in postmenopausal women: a pilot study

A pilot study investigated the effects of hormone replacement therapy (HRT) on sleep-disordered breathing (SDB) in six postmenopausal women with mild to moderate SDB. Polysomnography was conducted at baseline, after 7-12 days of estrogen therapy, and again after an additional 7-13 days of combined estrogen and progesterone therapy. Estrogen alone

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June 26, 2025 No Comments

Serum estrogen level after hormone replacement therapy and body mass index in postmenopausal and bilaterally ovariectomized women

This observational study examined the relationship between serum estrogen levels after hormone replacement therapy (HRT) and body mass index (BMI) in postmenopausal and bilaterally ovariectomized women. It found that daily HRT administration led to a significant positive correlation between serum estradiol levels and BMI (P < 0.05 and P <

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June 26, 2025 No Comments

Six-month oral dehydroepiandrosterone supplementation in early and late postmenopause

This randomized controlled trial investigated the effects of six-month oral dehydroepiandrosterone (DHEA) supplementation (50 mg/day) on hormonal levels, adrenal function, and menopausal symptoms in early and late postmenopausal women. The study found significant increases in circulating androgens, estrogens, and beta-endorphins, along with decreased cortisol and gonadotropins. Participants experienced improved menopausal

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June 26, 2025 No Comments

Testosterone dose-response relationships in hysterectomized women with or without oophorectomy: effects on sexual function, body composition, muscle performance and physical function in a randomized trial

Testosterone therapy in hysterectomized postmenopausal women was studied in a randomized controlled trial examining its effects on sexual function, body composition, muscle performance, and physical function over 24 weeks. 71 participants received weekly intramuscular injections of placebo or testosterone enanthate (3, 6.25, 12.5, or 25 mg). The results showed dose-dependent

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June 26, 2025 No Comments

Testosterone for low libido

This commentary discusses a study on testosterone therapy for low libido in postmenopausal women not taking estrogen, highlighting its potential to increase sexual desire and the frequency of satisfying sexual episodes. The study found significant improvements in libido among women receiving testosterone, suggesting its efficacy in this population. The mechanism

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June 26, 2025 No Comments

Testosterone for low libido in postmenopausal women not taking estrogen

This randomized controlled trial assessed the efficacy and safety of transdermal testosterone therapy in 814 postmenopausal women with hypoactive sexual desire disorder (HSDD) not receiving estrogen therapy. Over 52 weeks, participants received 150 μg or 300 μg of testosterone per day, or a placebo, with the 300 μg dose significantly

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June 26, 2025 No Comments

Testosterone for Treating Female Sexual Dysfunction

This review article examines the role of testosterone therapy in treating female sexual dysfunction, particularly hypoactive sexual desire disorder (HSDD) in postmenopausal women. It highlights clinical trial evidence showing improvements in sexual desire, arousal, orgasm, and the frequency of satisfying sexual events with testosterone therapy. When administered at physiological levels,

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June 26, 2025 No Comments