This randomized controlled trial investigated the effects of six-month oral dehydroepiandrosterone (DHEA) supplementation (50 mg/day) on hormonal levels, adrenal function, and menopausal symptoms in early and late postmenopausal women. The study found significant increases in circulating androgens, estrogens, and beta-endorphins, along with decreased cortisol and gonadotropins. Participants experienced improved menopausal