Well Referenced

Tag: ozone therapy

Effectiveness of intradiscal ozone injections for treating pain following herniated lumbar disc: A systematic review and meta-analysis

This meta-analysis evaluated the effectiveness of intradiscal ozone injections for treating pain caused by herniated lumbar discs (HLDs). The results showed that ozone injections provided superior pain relief compared to steroid injections and conventional medications, with significant improvements in pain scores at both 6 and 12 months. The therapy demonstrated

Read More »
June 26, 2025 No Comments

Ozonated Oils and Cutaneous Wound Healing

This 2019 systematic review titled “Ozonated Oils and Cutaneous Wound Healing” (Current Pharmaceutical Design, DOI: [10.2174/1381612825666190702100504*) examined numerous experimental and clinical studies on the use of ozonated oils in wound healing. The findings highlight ozonated oils’ potent antimicrobial properties (bactericidal, antiviral, and antifungal), as well as their ability to modulate

Read More »
June 26, 2025 No Comments

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

This 2019 retrospective observational study titled “The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain” (Pain Practice, DOI: [10.1111/papr.12812*) evaluated the impact of paravertebral ozone/oxygen injections on 62 patients with chronic low back pain. Patients received 50 mL of a 15 µg/mL ozone mixture weekly for

Read More »
June 26, 2025 No Comments

Effects of Major Ozone Autohemotherapy on Physical Functionality and Quality of Life in Fibromyalgia Syndrome: A Prospective Cross-sectional Study

This prospective cross-sectional study examined the effects of major ozone autohemotherapy (MAH) on patients with fibromyalgia syndrome (FMS). The treatment involved 13 sessions of ozonated blood therapy, which resulted in significant improvements in pain reduction, physical functionality, and quality of life as measured by the Fibromyalgia Impact Questionnaire (FIQ) and

Read More »
June 26, 2025 No Comments

Ozonated Oils as Antimicrobial Systems in Topical Applications. Their Characterization, Current Applications, and Advances in Improved Delivery Techniques

This 2020 systematic review titled “Ozonated Oils as Antimicrobial Systems in Topical Applications. Their Characterization, Current Applications, and Advances in Improved Delivery Techniques” (Molecules, DOI: [10.3390/molecules25020334*) explores the chemical properties, antimicrobial mechanisms, and evolving applications of ozonated oils in medical, cosmetic, and textile fields. The review highlights that ozonated oils

Read More »
June 26, 2025 No Comments

The effects of oxygen-ozone therapy on regulatory T-cell responses in multiple sclerosis patients

This 2021 observational study titled “The Effects of Oxygen-Ozone Therapy on Regulatory T-Cell Responses in Multiple Sclerosis Patients” (Cell Biology International, DOI: [10.1002/cbin.11589*) investigated how medical ozone therapy impacts immune regulation in patients with multiple sclerosis (MS). The study found that ozone therapy significantly increased the frequency and suppressive function

Read More »
June 26, 2025 No Comments

A New Treatment Strategy that Reduces Growth/Differentiation Factor-15 in Type-2 Diabetes Mellitus: Major Autohemotherapy: A Pilot Study

This pilot study evaluated the effects of major autohemotherapy with ozone infusion on reducing growth/differentiation factor-15 (GDF-15) and LDL cholesterol in patients with type-2 diabetes mellitus (T2DM). The treatment, administered twice weekly for 10 sessions, resulted in a significant reduction in GDF-15 and LDL cholesterol levels in the T2DM group,

Read More »
June 26, 2025 No Comments

Efficacy of comprehensive ozone therapy in diabetic foot ulcer healing.

This cohort study evaluated the effectiveness of comprehensive ozone therapy for healing diabetic foot ulcers (DFUs) in 200 patients aged 18-85. The ozone therapy group, which received ozone treatment alongside standard care, showed significantly faster wound healing, with complete wound closure in all patients within an average of 69.44 days.

Read More »
June 26, 2025 No Comments

Ozone and ozonated oils in skin diseases: a review

This 2010 systematic review titled “Ozone and ozonated oils in skin diseases: a review” (Mediators of Inflammation, DOI: [10.1155/2010/610418*) discusses the chemistry, therapeutic potential, and formulation considerations of ozonated oils for dermatological use. Highlighting the formation of ozonides and peroxides through the reaction of ozone with unsaturated triglycerides, the review

Read More »
June 26, 2025 No Comments