Tag: Immunology

Metabolic complications of obesity: inflated or inflamed?

This 2007 review by Chandalia and Abate explores the role of chronic low-grade inflammation in the development of metabolic complications associated with obesity, such as insulin resistance, type 2 diabetes, and cardiovascular disease. The authors discuss how adipose tissue in obese individuals secretes pro-inflammatory cytokines like TNF-α and IL-6, which

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Diet, Gut Microbiome and Epigenetics: Emerging Links with Inflammatory Bowel Diseases and Prospects for Management and Prevention

This 2017 review explores the complex interplay between diet, gut microbiota, and epigenetic mechanisms in the pathogenesis and management of inflammatory bowel diseases (IBD), including Crohn’s disease and ulcerative colitis. It highlights how Western diets, rich in saturated fats and refined carbohydrates, can induce gut dysbiosis and promote inflammation. Conversely,

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Can an anti-inflammatory diet be effective in preventing or treating viral respiratory diseases? A systematic narrative review

This systematic narrative review evaluates the potential role of anti-inflammatory diets in preventing or managing viral respiratory diseases, including COVID-19. The authors analyzed existing literature on dietary patterns such as the Mediterranean diet, which is rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, and their effects on

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A Comprehensive Review of the Triangular Relationship among Diet-Gut Microbiota-Inflammation

This 2024 review article explores the intricate interplay between diet, gut microbiota, and inflammation, emphasizing their collective impact on human health. The authors discuss how dietary components, such as fibers, fats, and polyphenols, influence the composition and function of the gut microbiota. In turn, the microbiota modulates inflammatory responses through

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Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc

This overview synthesizes findings from multiple systematic reviews assessing the anti-inflammatory effects of vitamin D, vitamin C, melatonin, and zinc in the context of COVID-19. The analysis indicates that while these nutraceuticals possess immunomodulatory properties, the evidence supporting their efficacy in reducing inflammation and improving clinical outcomes in COVID-19 patients

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Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19

This review article discusses the potential benefits of early nutritional interventions using zinc, selenium, and vitamin D to enhance antiviral resistance, particularly in the context of COVID-19. The authors highlight that deficiencies in these micronutrients can impair immune function and increase susceptibility to viral infections. Zinc is noted for its

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Effective Immune Functions of Micronutrients against SARS-CoV-2

This review article explores the role of essential micronutrients—specifically vitamins A, C, D, E, B-complex, and minerals like zinc, selenium, iron, and copper—in supporting immune function against SARS-CoV-2. The authors discuss how deficiencies in these nutrients can impair immune responses, leading to increased susceptibility to infections. Vitamin D is highlighted

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Essential sufficiency of zinc, ω-3 polyunsaturated fatty acids, vitamin D and magnesium for prevention and treatment of COVID-19, diabetes, cardiovascular diseases, lung diseases and cancer

This narrative review emphasizes the critical role of maintaining sufficient levels of zinc, omega-3 polyunsaturated fatty acids (PUFAs), vitamin D, and magnesium in preventing and managing chronic diseases such as COVID-19, diabetes, cardiovascular diseases, lung diseases, and cancer. The author discusses how deficiencies in these nutrients can impair immune function,

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