Well Referenced

Tag: Immunology

Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis

This systematic review and meta-analysis evaluated 13 randomized controlled trials involving 589 women with endometriosis to assess the efficacy of antioxidant vitamin supplementation (vitamins E, C, and D) on endometriosis-related pain. The findings revealed that supplementation with vitamins E and C significantly reduced chronic pelvic pain, dysmenorrhea, and dyspareunia. Specifically,

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June 26, 2025 No Comments

Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging

This study investigated the relationships between inflammatory markers, kynurenine pathway metabolites, B vitamins, age, and mortality in a cohort of 1,839 older adults. Results indicated that elevated levels of inflammatory markers and kynurenine pathway metabolites were associated with increased age and higher mortality risk. Conversely, higher concentrations of certain B

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June 26, 2025 No Comments

Baker’s yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk?

This randomized, double-blind, placebo-controlled crossover study evaluated the effects of a 10-day supplementation with baker’s yeast β-glucan (Wellmune WGP®) on immune responses following strenuous aerobic exercise in a hot, humid environment. Sixty recreationally active adults consumed either 250 mg/day of β-glucan or a placebo before performing a 49-minute cycling session.

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June 26, 2025 No Comments

Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial

This double-blind, randomized, placebo-controlled trial assessed the effects of a dairy-based beverage containing 250 mg of dispersible baker’s yeast β-glucan (Wellmune®) on upper respiratory tract infections (URTIs) in marathon runners. Participants consumed the beverage daily for 45 days before and after the marathon. While the number and duration of URTI

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June 26, 2025 No Comments

Daily Vitamin D Supplementation Prevents Some New Autoimmune Diseases

This randomized, double-blind, placebo-controlled trial assessed the effect of daily vitamin D supplementation (2,000 IU) on the incidence of autoimmune diseases in adults aged 50 and older. Over a median follow-up of 5.3 years, participants receiving vitamin D experienced a 22% reduction in confirmed autoimmune diseases compared to placebo. The

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June 26, 2025 No Comments