Well Referenced

Tag: Immunology

Zinc Supplementation Decreases Incidence of Infections in the Elderly: Effect of Zinc on Generation of Cytokines and Oxidative Stress

This 2007 randomized, double-blind, placebo-controlled trial, published in The American Journal of Clinical Nutrition, investigated the effects of zinc supplementation on infection incidence, cytokine production, and oxidative stress in elderly individuals. The study enrolled 50 healthy adults aged 55–87 years, who received either 45 mg/day of elemental zinc as zinc

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June 26, 2025 No Comments

Can an anti-inflammatory diet be effective in preventing or treating viral respiratory diseases? A systematic narrative review

This systematic narrative review evaluates the potential role of anti-inflammatory diets in preventing or managing viral respiratory diseases, including COVID-19. The authors analyzed existing literature on dietary patterns such as the Mediterranean diet, which is rich in fruits, vegetables, whole grains, lean proteins, and healthy fats, and their effects on

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June 26, 2025 No Comments

A Comprehensive Review of the Triangular Relationship among Diet-Gut Microbiota-Inflammation

This 2024 review article explores the intricate interplay between diet, gut microbiota, and inflammation, emphasizing their collective impact on human health. The authors discuss how dietary components, such as fibers, fats, and polyphenols, influence the composition and function of the gut microbiota. In turn, the microbiota modulates inflammatory responses through

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June 26, 2025 No Comments

Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc

This overview synthesizes findings from multiple systematic reviews assessing the anti-inflammatory effects of vitamin D, vitamin C, melatonin, and zinc in the context of COVID-19. The analysis indicates that while these nutraceuticals possess immunomodulatory properties, the evidence supporting their efficacy in reducing inflammation and improving clinical outcomes in COVID-19 patients

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June 26, 2025 No Comments

Vitamin B1, B2, B3, B5, and B6 and the Immune System

This article, published on ResearchGate, explores the roles of vitamins B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), and B6 (pyridoxine) in immune system function. It discusses how these water-soluble B vitamins contribute to various aspects of immune health, including energy metabolism, antioxidant defense, and the synthesis of immune-related

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June 26, 2025 No Comments

β‐Glucan supplementation, allergy symptoms, and quality of life in self‐described ragweed allergy sufferers

This 2013 randomized, double-blind, placebo-controlled study by Talbott et al., published in Food Science & Nutrition, examined the effects of daily supplementation with 250 mg of Wellmune WGP® β-1,3/1,6-glucan over four weeks in self-described moderate ragweed allergy sufferers. Compared to the placebo group, participants receiving β‐glucan experienced significant reductions in

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June 26, 2025 No Comments

A New Mechanism of Vitamin C Effects on A/FM/1/47(H1N1) Virus-Induced Pneumonia in Restraint-Stressed Mice

This 2015 study by Cai et al., published in BioMed Research International, investigated the effects of vitamin C on influenza-induced pneumonia in restraint-stressed mice. The research demonstrated that restraint stress heightened mortality and pneumonia severity following A/FM/1/47 (H1N1) infection. Oral administration of vitamin C (125 and 250 mg/kg) significantly improved

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June 26, 2025 No Comments

Influence of Vitamin C on Lymphocytes: An Overview

This review article explores the role of vitamin C (ascorbic acid) in the development and function of lymphocytes, particularly in the context of cancer treatment. It highlights that vitamin C is essential for T cell development and may enhance T cell proliferation and function. The effects on B lymphocytes are

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June 26, 2025 No Comments

Association of Markers of Inflammation, the Kynurenine Pathway and B Vitamins with Age and Mortality, and a Signature of Inflammaging

This study investigated the relationships between inflammatory markers, kynurenine pathway metabolites, B vitamins, age, and mortality in a cohort of 1,839 older adults. Results indicated that elevated levels of inflammatory markers and kynurenine pathway metabolites were associated with increased age and higher mortality risk. Conversely, higher concentrations of certain B

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June 26, 2025 No Comments

Baker’s yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk?

This randomized, double-blind, placebo-controlled crossover study evaluated the effects of a 10-day supplementation with baker’s yeast β-glucan (Wellmune WGP®) on immune responses following strenuous aerobic exercise in a hot, humid environment. Sixty recreationally active adults consumed either 250 mg/day of β-glucan or a placebo before performing a 49-minute cycling session.

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June 26, 2025 No Comments