Well Referenced

Tag: fatigue

Sports massage with ozonised oil or non-ozonised oil: Comparative effects on recovery parameters after maximal effort in cyclists

This 2013 study by Paoli et al. evaluated the effects of sports massage using ozonised oil (SMOZO) versus non-ozonised oil (SM) and passive rest (PR) on recovery in 15 male competitive cyclists. Following three pre-fatiguing Wingate tests, participants underwent one of the three recovery interventions. Measurements included power output (P),

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June 26, 2025 No Comments

Sjögren syndrome successfully treated with oxygen-ozone auto-hemotherapy (O2-O3-AHT): a case report

This 2022 case report details the treatment of a 69-year-old female patient with primary Sjögren syndrome (SS) using oxygen-ozone autohemotherapy (O2-O3-AHT). The patient, presenting with ocular dryness, fatigue, and pain, underwent two cycles of three O2-O3-AHT sessions between December 2020 and January 2021. Post-treatment, she experienced rapid symptom relief without

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June 26, 2025 No Comments

Study and treatment of post Lyme disease (STOP-LD): a randomized double masked clinical trial

This 2003 single-center, randomized, double-masked, placebo-controlled trial evaluated the efficacy of intravenous ceftriaxone in 55 patients with post-Lyme syndrome (PLS) experiencing severe fatigue persisting for at least six months post-treatment. Participants received either 28 days of IV ceftriaxone or placebo. The primary outcome was improvement in fatigue, assessed via an

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June 26, 2025 No Comments

Intravenous Vitamin C Administration Improves Quality of Life in Breast Cancer Patients During Chemo-/Radiotherapy and Aftercare: Results of a Retrospective, Multicentre, Epidemiological Cohort Study in Germany

This 2011 retrospective multicenter cohort study evaluated the safety and efficacy of intravenous vitamin C (IVC) administration in 125 women with breast cancer (UICC stages IIa–IIIb) during the first postoperative year. Fifty-three patients received 7.5 g IVC weekly alongside standard chemo-/radiotherapy, while 72 served as controls. The IVC group experienced

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June 26, 2025 No Comments

Impact of Intravenous Vitamin C Administration in Reducing Severity of Symptoms in Breast Cancer Patients During Treatment

This single-center, single-blind, randomized controlled trial conducted in Pakistan assessed the effects of intravenous vitamin C (IVC) on symptom severity in 350 breast cancer patients (stages IIA–IIIb) undergoing standard treatment. Participants were randomized to receive either 25g/week of IVC or placebo over four weeks. The IVC group showed statistically significant

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June 26, 2025 No Comments

Fatigue in post-acute sequelae of SARS-CoV2 (PASC) treated with oxygen-ozone autohemotherapy – preliminary results on 100 patients

This study explored the efficacy of oxygen-ozone autohemotherapy (O2-O3-AHT) for treating fatigue in patients suffering from post-acute sequelae of SARS-CoV2 (PASC), also known as long COVID. The trial involved 100 patients and found that O2-O3-AHT resulted in a 67% reduction in fatigue, with 40% of patients experiencing complete recovery. The

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June 26, 2025 No Comments

Quality of Life of Patients With Advanced Pancreatic Cancer During Treatment With Mistletoe: A Randomized Controlled Trial

This randomized controlled trial evaluated the impact of mistletoe extract on the quality of life (QoL) in 220 patients with advanced pancreatic cancer who were receiving best supportive care. The study found significant improvements in physical well-being, particularly in reducing fatigue, for those receiving mistletoe extract. Mistletoe was administered via

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June 26, 2025 No Comments

Ginseng and health outcomes: an umbrella review

This umbrella review analyzed 19 meta-analyses to assess the health benefits of ginseng supplementation, which showed improvements in various conditions such as fatigue, physical function, sexual function, menopausal symptoms, metabolic indicators, inflammatory markers, unstable angina, and respiratory diseases. While ginseng exhibited positive effects compared to placebo controls, the review highlighted

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June 26, 2025 No Comments

Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms–results of an open-label study

This open-label observational study assessed the effects of Rhodiola rosea extract WS® 1375 on individuals with life-stress symptoms. A total of 101 participants took 200 mg of the extract twice daily for four weeks. Improvements in stress, fatigue, functional impairment, and overall well-being were observed as early as day 3

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June 26, 2025 No Comments

Intravenous Micronutrient Therapy (Myers’ Cocktail) for Fibromyalgia: A Placebo-Controlled Pilot Study

This randomized, double-blind, placebo-controlled pilot study evaluated the safety, feasibility, and preliminary efficacy of intravenous micronutrient therapy (IVMT), specifically the Myers’ Cocktail, in 34 adults with ACR-defined fibromyalgia. Participants received weekly infusions of either IVMT or placebo over 8 weeks. Both groups showed within-group improvements, but no statistically significant differences

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June 26, 2025 No Comments