This review article on Iron Deficiency Anemia (IDA) outlines its widespread prevalence, particularly due to menstrual blood loss and gastrointestinal bleeding. It emphasizes that iron deficiency impacts more than hemoglobin levels, leading to symptoms like fatigue, hair loss, and restless legs syndrome. Serum ferritin is identified as the most accurate
This randomized controlled trial examined the effects of intravenous L-carnitine supplementation on fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome. Participants receiving 4 g/day of intravenous L-carnitine experienced significantly greater weight loss (-4.6 ± 0.9 kg vs. -3.2 ± 1.1 kg, P = 0.03), reductions in waist
This article explores the use of high-dose intravenous vitamin C as an adjunct treatment for cancer patients, showing that it can significantly reduce cancer-related symptoms like pain, fatigue, and nausea, while also improving overall well-being. The therapy is non-toxic, with few mild side effects such as temporary diarrhea and fatigue.
This randomized controlled trial examined the effects of intravenous L-carnitine supplementation on fatigue and exercise capacity in patients with end-stage renal disease (ESRD) undergoing hemodialysis. Patients received L-carnitine at doses of 10 mg/kg, 20 mg/kg, or 40 mg/kg thrice weekly for 24 weeks. While primary analysis showed no significant improvement
A meta-analysis of 11 randomized controlled trials involving 1,216 patients evaluated the effectiveness of thyroxine (T4) monotherapy compared to combination therapy with thyroxine and triiodothyronine (T3) in treating clinical hypothyroidism. The study found no significant differences between the two treatment approaches in alleviating symptoms such as bodily pain, depression, anxiety,
A systematic review and meta-analysis compared the effectiveness and safety of combined levothyroxine (LT4) and L-triiodothyronine (LT3) therapy versus LT4 monotherapy in adults with hypothyroidism. The study found no significant differences in clinical outcomes, including quality of life, psychological distress, depressive symptoms, and fatigue, between the two treatment methods. However,
The systematic review titled “Dehydroepiandrosterone (DHEA) Supplementation in Rheumatic Diseases” (Mediterranean Journal of Rheumatology, 2023, DOI: 10.31138/mjr.20230825.dd) evaluated the effectiveness of DHEA in patients with systemic lupus erythematosus (SLE), Sjögren’s syndrome (SS), rheumatoid arthritis (RA), and fibromyalgia (FM) across 21 studies. DHEA supplementation notably improved bone mineral density, reduced fatigue,
This systematic review analyzed ten clinical studies, including randomized controlled trials and observational studies, to evaluate the effects of hyperbaric oxygen therapy (HBOT) on long COVID symptoms. The findings suggest that HBOT may improve quality of life, fatigue, cognition, neuropsychiatric symptoms, and cardiopulmonary function in long COVID patients. However, the
This observational study investigated the effects of hyperbaric oxygen therapy (HBOT) on individuals suffering from long COVID symptoms, particularly fatigue and cognitive dysfunction. Ten participants received 10 HBOT sessions over 12 days, which led to significant improvements in fatigue, executive function, attention, information processing, and verbal function. While no adverse
