Nutritional support for disease prevention and cellular health.
This comprehensive 2014 review by Gupta et al. explores the therapeutic applications of zinc in dermatology, encompassing both topical and oral formulations. Zinc’s anti-inflammatory, antioxidant, immunomodulatory, and antimicrobial properties underpin its efficacy in various skin conditions. In acne vulgaris, oral zinc sulfate and gluconate have demonstrated benefits, particularly in inflammatory
This review article discusses the potential benefits of early nutritional interventions using zinc, selenium, and vitamin D to enhance antiviral resistance, particularly in the context of COVID-19. The authors highlight that deficiencies in these micronutrients can impair immune function and increase susceptibility to viral infections. Zinc is noted for its
This 2012 review article, published in Current Pharmaceutical Design, explores the involvement of oxidative stress in the pathophysiology of depressive disorders. The authors discuss how an imbalance between reactive oxygen species (ROS) production and antioxidant defenses can lead to neuronal damage, contributing to the development and progression of depression. The
This 2024 systematic review and meta-analysis, published in PLOS ONE, evaluated the efficacy of vitamin C and E supplementation in reducing pain symptoms associated with endometriosis. The analysis included randomized controlled trials that assessed the impact of these antioxidants on endometriosis-related pain. The findings suggest that supplementation with vitamins C
This 1991 study by Trizna et al., published in The American Journal of Surgery, investigated the protective effects of N-acetyl-L-cysteine (NAC) and ascorbic acid (vitamin C) against mutagen-induced chromosomal damage in patients with head and neck cancers. Using the bleomycin-induced chromosomal breakage assay, the researchers assessed chromosomal sensitivity in lymphocytes
This systematic review evaluated 39 reports from 37 studies, including 2 randomized controlled trials, 15 uncontrolled trials, 6 observational studies, and 14 case reports, to assess the safety, effectiveness, and pharmacokinetics of intravenous vitamin C (IVC) in cancer patients. The review found that IVC is generally well-tolerated and does not
This 2018 review explores the role of intravenous vitamin C (IVC) in supporting cancer patients. It highlights that cancer patients often have low vitamin C levels due to factors like poor intake and increased oxidative stress. The article discusses IVC’s potential benefits, including reducing inflammation, alleviating treatment-related side effects, and
This randomized, placebo-controlled trial assessed the impact of antioxidant vitamins E (1200 IU) and C (1000 mg) administered daily for 8 weeks in 59 women aged 19–41 with pelvic pain and a history of endometriosis or infertility. The antioxidant group experienced significant reductions in chronic pelvic pain (43%), dysmenorrhea (37%),
This systematic review and meta-analysis evaluated 13 randomized controlled trials involving 589 women with endometriosis to assess the efficacy of antioxidant vitamin supplementation (vitamins E, C, and D) on endometriosis-related pain. The findings revealed that supplementation with vitamins E and C significantly reduced chronic pelvic pain, dysmenorrhea, and dyspareunia. Specifically,
This meta-analysis of 26 studies involving 5,633 COVID-19 patients evaluated the effects of vitamin C, vitamin D, and zinc supplementation on clinical outcomes. Vitamin C supplementation showed no significant impact on mortality, intubation rates, or length of hospital stay (LOS). Vitamin D supplementation did not reduce mortality but was associated
