Well Referenced

Category: Vitamins, Supplements & Antioxidants

Nutritional support for disease prevention and cellular health.

Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis

This systematic review and meta-analysis evaluated 13 randomized controlled trials involving 589 women with endometriosis to assess the efficacy of antioxidant vitamin supplementation (vitamins E, C, and D) on endometriosis-related pain. The findings revealed that supplementation with vitamins E and C significantly reduced chronic pelvic pain, dysmenorrhea, and dyspareunia. Specifically,

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June 26, 2025 No Comments

Oxygen-ozone autohemotherapy in breast cancer patients suffering from fatigue and musculoskeletal pain upon aromatase inhibitors treatment: a case-series study

This review investigates the molecular impacts of ozone on hemoglobin and albumin, particularly in the context of major ozonated autohemotherapy. It explains that ozone dissolves in plasma and reacts rapidly with biomolecules to produce hydrogen peroxide and lipid oxidation products (LOPs), which serve as signaling molecules. These messengers can trigger

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June 26, 2025 No Comments

Preventive Migraine Treatment

This 2015 observational study published in Nutrition Research analyzed data from 9,148 U.S. adults aged 40 and older using NHANES 2005–2010 to examine the relationship between dietary magnesium intake, C-reactive protein (CRP), and the prevalence of metabolic syndrome (MetS). The study found that individuals in the highest quintile of magnesium

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June 26, 2025 No Comments

Role of Magnesium in the Pathogenesis and Treatment of Migraine

This 2009 prospective cohort study published in Diabetes Care used data from 4,497 adults in the ARIC study to examine the relationship between magnesium status and the risk of developing type 2 diabetes over a median follow-up of 6 years. Participants in the highest quintile of magnesium intake had a

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June 26, 2025 No Comments

The 3Mg trial: a randomised controlled trial of intravenous or nebulised magnesium sulphate versus placebo in adults with acute severe asthma

This 2014 cohort study published in the American Journal of Clinical Nutrition analyzed data from 13,504 U.S. adults in NHANES III to examine the association between magnesium intake and liver disease mortality over a follow-up period through 2006. The study found that individuals with higher magnesium intake had a significantly

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June 26, 2025 No Comments

The effects of magnesium prophylaxis in migraine without aura

This 2008 prospective cohort study published in the American Journal of Epidemiology analyzed data from 58,615 Japanese adults in the Japan Public Health Center-based Study Cohort I to evaluate the association between dietary magnesium intake and stroke risk over an average follow-up of 10.7 years. Among men, higher magnesium intake

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June 26, 2025 No Comments

The effects of multivitamin supplementation on mood and general well-being in healthy young adults. A laboratory and at-home mobile phone assessment

This 2013 cohort study published in the American Journal of Clinical Nutrition analyzed data from 13,504 U.S. adults in NHANES III to examine the relationship between magnesium intake and liver disease mortality over a follow-up period through 2006. The study found that each 100 mg/day increase in magnesium intake was

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June 26, 2025 No Comments

Usefulness of Nutraceuticals in Migraine Prophylaxis

This article provides a review of the use of nutraceuticals, including magnesium, riboflavin, coenzyme Q10, feverfew, and butterbur, for migraine prophylaxis. It highlights the growing body of evidence supporting the efficacy of these non-pharmacological treatments in reducing the frequency and severity of migraines, especially for patients dissatisfied with conventional medications.

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June 26, 2025 No Comments

Why All Migraine Patients Should Be Treated With Magnesium

This article emphasizes the critical role of magnesium in migraine management, advocating for its routine use in all migraine patients due to its potential to reduce migraine frequency and intensity. Magnesium is involved in several processes that may influence migraine pathogenesis, including cortical spreading depression, platelet aggregation, and serotonin receptor

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June 26, 2025 No Comments