Well Referenced

Category: Inflammation & Autoimmune Health

Immune system regulation, chronic inflammation management, and prevention.

Potential health benefits of zinc supplementation for the management of COVID-19 pandemic

This review article explores the potential role of zinc supplementation in managing the COVID-19 pandemic. It highlights zinc’s essential functions in immune modulation, antiviral defense, and anti-inflammatory responses. The authors discuss zinc’s ability to inhibit viral replication by interfering with viral genome transcription and protein translation, as well as its

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June 26, 2025 No Comments

Self-Care for Common Colds: The Pivotal Role of Vitamin D, Vitamin C, Zinc, and Echinacea in Three Main Immune Interactive Clusters (Physical Barriers, Innate and Adaptive Immunity) Involved during an Episode of Common Colds—Practical Advice on Dosages and on the Time to Take These Nutrients/Botanicals in order to Prevent or Treat Common Colds

This 2018 narrative review by Rondanelli et al., published in Evidence-Based Complementary and Alternative Medicine, synthesizes findings from 82 studies to evaluate the roles of vitamin D, vitamin C, zinc, and Echinacea in supporting immune function across three key domains: physical barriers, innate immunity, and adaptive immunity. The authors report

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June 26, 2025 No Comments

Does Evidence Exist to Blunt Inflammatory Response by Nutraceutical Supplementation during COVID-19 Pandemic? An Overview of Systematic Reviews of Vitamin D, Vitamin C, Melatonin, and Zinc

This overview synthesizes findings from multiple systematic reviews assessing the anti-inflammatory effects of vitamin D, vitamin C, melatonin, and zinc in the context of COVID-19. The analysis indicates that while these nutraceuticals possess immunomodulatory properties, the evidence supporting their efficacy in reducing inflammation and improving clinical outcomes in COVID-19 patients

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June 26, 2025 No Comments

Role of Zinc in Immune System and Anti-Cancer Defense Mechanisms

This comprehensive review explores the multifaceted role of zinc in modulating immune responses and its potential anti-cancer properties. Zinc is integral to numerous physiological processes, including the function of over 300 enzymes and various transcription factors, notably through structures like zinc fingers that facilitate DNA binding. The article highlights that

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June 26, 2025 No Comments

Trace Element Zinc and Skin Disorders

This 2023 review article by Zou et al., published in Frontiers in Medicine, examines the multifaceted roles of zinc in skin health and its involvement in various dermatological conditions. Zinc is crucial for maintaining skin integrity, modulating inflammation, and supporting immune responses. The review discusses zinc’s involvement in skin disorders

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June 26, 2025 No Comments

Zinc against COVID-19? Symptom Surveillance and Deficiency Risk Groups

This 2021 review article by Marcin P. Joachimiak, published in PLoS Neglected Tropical Diseases, explores the potential role of zinc in mitigating COVID-19 symptoms and identifies populations at risk for zinc deficiency. The author discusses zinc’s critical functions in immune response modulation, antiviral activity, and maintenance of mucosal integrity. The

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June 26, 2025 No Comments

Cognitive Behavioral Therapy and Tai Chi Reverse Cellular and Genomic Markers of Inflammation in Late-Life Insomnia: A Randomized Controlled Trial

This 2015 randomized controlled trial by Irwin et al. investigated the effects of cognitive behavioral therapy for insomnia (CBT-I) and Tai Chi Chih (TCC) on inflammation in 123 older adults with chronic insomnia. Participants were assigned to CBT-I, TCC, or a sleep seminar (SS) control group, attending weekly 2-hour sessions

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June 26, 2025 No Comments

Zinc for the Treatment of the Common Cold: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

This 2012 systematic review and meta-analysis, published in the Canadian Medical Association Journal, evaluated the efficacy and safety of oral zinc formulations in treating the common cold. The study included 17 randomized controlled trials with a total of 2,121 participants. Results indicated that zinc supplementation reduced the duration of cold

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June 26, 2025 No Comments