This 2017 narrative review titled "Therapeutic Relevance of Ozone Therapy in Degenerative Diseases: Focus on Diabetes and Spinal Pain" (Journal of Cellular Physiology, DOI: [10.1002/jcp.26044]*) critically examined how controlled, low-dose ozone therapy activates key molecular pathways including HIF-1α, NFAT, Nrf2-ARE, and AP-1, leading to upregulation of antioxidant defenses, modulation of
