The Effect of an EDTA-based Chelation Regimen on Patients With Diabetes Mellitus and Prior Myocardial Infarction in the Trial to Assess Chelation Therapy (TACT)

This randomized controlled trial from the Trial to Assess Chelation Therapy (TACT) evaluated the effects of EDTA-based chelation therapy in 1,708 patients aged 50 years or older with a history of myocardial infarction (MI), including 633 with diabetes mellitus. Over five years, chelation therapy significantly reduced major cardiovascular events in