Tag: diabetes mellitus

Treatment of Diabetic Impotence with Umbilical Cord Blood Stem Cell Intracavernosal Transplant: Preliminary Report of 7 Cases

This 2010 pilot study assessed the safety and efficacy of intracavernosal injections of human umbilical cord blood stem cells (hUCBSCs) in seven male patients (ages 57–87) with type 2 diabetes mellitus and refractory erectile dysfunction (ED). Each patient received a single injection of 1.5×10⁷ hUCBSCs without immunosuppression. Over a 9-month

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The Effect of Intracavernosal Injection of Stem Cell in the Treatment of Erectile Dysfunction in Diabetic Patients: A Randomized Single-blinded Clinical Trial

This 2021 randomized, single-blind clinical trial evaluated the safety and efficacy of intracavernosal injection of autologous oral mucosa-derived mesenchymal stem cells (MSCs) in 20 diabetic men with erectile dysfunction (ED) unresponsive to standard treatments. Participants were divided into intervention (n=10) and control (n=10) groups. The intervention group received a single

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The Efficacy of Li-ESWT Combined With VED in Diabetic ED Patients Unresponsive to PDE5is: A Single-Center, Randomized Clinical Trial

This 2022 randomized clinical trial assessed the efficacy of combining low-intensity extracorporeal shock wave therapy (Li-ESWT) with vacuum erectile device (VED) therapy in 105 diabetic men with erectile dysfunction (ED) unresponsive to phosphodiesterase type 5 inhibitors (PDE5is). Participants were divided into three groups: VED alone, Li-ESWT alone, and combined VED

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Daily Oral l-Arginine Plus Tadalafil in Diabetic Patients with Erectile Dysfunction: A Double-Blinded, Randomized, Controlled Clinical Trial

This 2019 double-blind, randomized controlled trial evaluated the efficacy of daily oral l-arginine (2.5 g) combined with tadalafil (5 mg) in 108 diabetic men with mild to moderate erectile dysfunction (ED). Over an 8-week period, patients receiving the combination therapy exhibited significant improvements in International Index of Erectile Function-5 (IIEF-5)

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Safety and Efficacy of 2 Intracavernous Injections of Allogeneic Wharton’s Jelly-Derived Mesenchymal Stem Cells in Diabetic Patients with Erectile Dysfunction: Phase 1/2 Clinical Trial

This 2021 phase 1/2 clinical trial evaluated the safety and efficacy of two intracavernous injections of allogeneic Wharton’s jelly-derived mesenchymal stem cells (WJ-MSCs) in 22 diabetic men with refractory erectile dysfunction (ED). The procedure was well-tolerated, with only minimal and transient adverse events such as redness and bruising at the

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Relations of plasma high-sensitivity C-reactive protein to traditional cardiovascular risk factors

This observational study, published in Atherosclerosis (DOI: 10.1016/s0021-9150(02)00380-5), explored the relationship between plasma high-sensitivity C-reactive protein (hsCRP) levels and traditional cardiovascular risk factors in 908 participants aged 30-79. The study found that hsCRP levels were significantly higher in individuals with hypertension, diabetes, or coronary artery disease, and multiple regression analysis

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