The Effect of 600 mg Alpha-lipoic Acid Supplementation on Oxidative Stress, Inflammation, and RAGE in Older Adults with Type 2 Diabetes Mellitus

This quasi-experimental study examined the effects of 600 mg/day alpha-lipoic acid (ALA) supplementation for six months on oxidative stress, inflammation, and RAGE levels in 135 sedentary older adults with type 2 diabetes mellitus (T2DM). The study found a statistically significant decrease (p < 0.05) in 8-isoprostane levels and RAGE concentrations