This 2015 preclinical study by Kanashiro-Takeuchi et al. investigated the effects of growth hormone-releasing hormone (GHRH) agonists on myocardial infarction (MI)-induced heart failure. Using rodent models, the researchers administered GHRH agonists (JI-38, MR-356, and MR-409) and observed significant improvements in cardiac function, including reduced infarct size, enhanced vascular density, increased
